To determine whether an automated extraction of the brain-tissue region from CT\nimages is useful for the histogram analysis of the brain-tissue region was studied. We\nused the CT images of 11 patients. We developed an automatic brain-tissue extraction\nalgorithm. We evaluated the similarity index of this automated extraction method\nrelative to manual extraction, and we compared the mean CT number of all extracted\npixels and the kurtosis and skewness of the distribution of CT numbers of all extracted\npixels from the automated and manual extractions. The similarity index was 0.93. The\nmean CT number and the kurtosis and skewness from the automated extraction were\n35.0 Hounsfield units, 0.63, and 0.51, respectively, and were equivalent to those from\nthe manual extraction (35.4 Hounsfield units, 0.59, and 0.46, respectively). The automated\nextraction of the brain-tissue region from whole-brain CT images was useful for\nhistogram analysis of the brain-tissue region.
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